Search on: CORE BINDING FACTORS 
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Descriptor English:   Core Binding Factors 
Descriptor Spanish:   Factores de Unión al Sitio Principal 
Descriptor Portuguese:   Fatores de Ligação ao Core 
Tree Number:   D12.776.930.155
Definition English:   Heterodimeric transcription factors containing a DNA-binding alpha subunits, (CORE BINDING FACTOR ALPHA SUBUNITS), along with a non-DNA-binding beta subunits, CORE BINDING FACTOR BETA SUBUNIT. Core Binding Factor regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression. 
Indexing Annotation English:   see SCR for organism-specific terms
History Note English:   2006(1997) 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   51174 
Unique Identifier:   D050660 

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