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CRK-ASSOCIATED SUBSTRATE PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
Crk-Associated Substrate Protein
Descriptor
Spanish
:
Proteína Sustrato Asociada a CrK
Descriptor
Portuguese
:
Proteína Substrato Associada a Crk
Tree Number:
D12.644.360.024.295
D12.776.157.057.022
D12.776.476.024.374
D12.776.744.425
Definition
English
:
Crk-associated substrate was originally identified as a highly phosphorylated 130 kDa protein that associates with ONCOGENE PROTEIN CRK and ONCOGENE PROTEIN SRC. It is a signal transducing adaptor protein that undergoes
tyrosine
PHOSPHORYLATION
in signaling pathways that regulate CELL
MIGRATION
and
CELL PROLIFERATION.
History Note
English
:
2006(2004)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
50765
Unique Identifier:
D050719
Occurrence in VHL
:
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