Search on: CRUSH SYNDROME 
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Descriptor English:   Crush Syndrome 
Descriptor Spanish:   Síndrome de Aplastamiento 
Descriptor Portuguese:   Síndrome de Esmagamento 
Tree Number:   C21.866.797.240
Definition English:   Severe systemic manifestation of trauma and ischemia involving soft tissues, principally skeletal muscle, due to prolonged severe crushing. It leads to increased permeability of the cell membrane and to the release of potassium, enzymes, and myoglobin from within cells. Ischemic renal dysfunction secondary to hypotension and diminished renal perfusion results in acute tubular necrosis and uremia. 
See Related English:   Compartment Syndromes
 
History Note English:   91(75); was see under SHOCK, TRAUMATIC 1979-90; was see under KIDNEY FAILURE, ACUTE 1967-78; was see under ACUTE RENAL FAILURE 1963-66 
Allowable Qualifiers English:  
blood cerebrospinal fluid
chemically induced classification
congenital complications
diet therapy diagnosis
drug therapy economics
ethnology embryology
enzymology epidemiology
etiology genetics
history immunology
metabolism microbiology
mortality nursing
pathology prevention & control
physiopathology parasitology
psychology radiography
rehabilitation radionuclide imaging
radiotherapy surgery
therapy urine
ultrasonography veterinary
virology  
Record Number:   3461 
Unique Identifier:   D003444 

Occurrence in VHL:
 

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