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CYCLIN-DEPENDENT KINASE INHIBITOR P21
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DeCS
Descriptor
English
:
Cyclin-Dependent Kinase Inhibitor p21
Descriptor
Spanish
:
Inhibidor p21 de las Quinasas Dependientes de la Ciclina
Descriptor
Portuguese
:
Inibidor de Quinase Dependente de Ciclina p21
Tree Number:
D12.644.360.225.500
D12.776.167.187.500
D12.776.476.225.500
D12.776.624.776.355.500
Definition
English
:
A cyclin-dependent kinase inhibitor that mediates TUMOR SUPRESSOR PROTEIN P53-dependent
CELL CYCLE
arrest. p21 interacts with a range of
CYCLIN-DEPENDENT KINASES
and associates with
PROLIFERATING CELL NUCLEAR ANTIGEN
and
CASPASE 3.
Pharmacological Action:
Protein Kinase Inhibitors
History Note
English
:
2006(1993)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
50931
Unique Identifier:
D050759
Occurrence in VHL
:
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