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CYCLOSPORIN A
Descriptors Found:
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DeCS
Descriptor
English
:
Cyclosporine
Descriptor
Spanish
:
Ciclosporina
Descriptor
Portuguese
:
Ciclosporina
Synonyms
English
:
Cyclosporin A
Tree Number:
D04.345.566.235.300
D12.644.641.235.300
Definition
English
:
A cyclic undecapeptide from an extract of
soil
fungi
. It is a powerful immunosupressant with a specific action on
T-lymphocytes
. It is used for the prophylaxis of
graft rejection
in organ and
tissue transplantation
. (From Martindale, The Extra Pharmacopoeia, 30th ed).
Indexing Annotation
English
:
a specific drug: do not confuse this or X ref with
CYCLOSPORINS
Pharmacological Action:
Antifungal Agents
Antirheumatic Agents
Dermatologic Agents
Enzyme Inhibitors
Immunosuppressive Agents
Entry Combination - descr/qualif
English
:
Cyclosporine
/
analogs & derivatives
use
Cyclosporins
History Note
English
:
92; for CYCLOSPORIN A use CYCLOSPORINS 1982-91
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
urine
Record Number:
30164
Unique Identifier:
D016572
Occurrence in VHL
:
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