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CYCLOSPORINS
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DeCS
Descriptor
English
:
Cyclosporins
Descriptor
Spanish
:
Ciclosporinas
Descriptor
Portuguese
:
Ciclosporinas
Tree Number:
D04.345.566.235
D12.644.641.235
Definition
English
:
A group of closely related cyclic undecapeptides from the
fungi
Trichoderma
polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects.
Cyclosporins
have been proposed as adjuvants in tissue and
organ transplantation
to suppress
graft rejection.
Indexing Annotation
English
:
immunosuppressants; do not confuse with
CYCLOSPORINE
, a specific drug, or its X ref CYCLOSPORIN
Pharmacological Action:
Enzyme Inhibitors
Immunosuppressive Agents
History Note
English
:
82
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
3544
Unique Identifier:
D003524
Occurrence in VHL
:
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