Search on: DNA HELICASES 
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Descriptor English:   DNA Helicases 
Descriptor Spanish:   ADN Helicasas 
Descriptor Portuguese:   DNA Helicases 
Synonyms English:   DNA Unwinding Proteins  
Tree Number:   D08.811.277.040.025.159
D08.811.399.340
Definition English:   Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening. In addition DNA helicases are DNA-dependent ATPases that harness the free energy of ATP hydrolysis to translocate of DNA strands. 
Indexing Annotation English:   do not confuse entry term DNA UNWINDING PROTEINS with DNA UNTWISTING PROTEINS
History Note English:   1994 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   31824 
Unique Identifier:   D004265 

Occurrence in VHL:
 

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