Search on: DNA JOINASES 
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Descriptor English:   DNA Ligases 
Descriptor Spanish:   ADN Ligasas 
Descriptor Portuguese:   DNA Ligases 
Synonyms English:   DNA Joinases
Polydeoxyribonucleotide Ligases
Polydeoxyribonucleotide Synthetases  
Tree Number:   D08.811.074.500
D08.811.464.754.600
Definition English:   Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of preformed deoxyribonucleotides in phosphodiester linkage during genetic processes during repair of a single-stranded break in duplex DNA. The class includes both EC 6.5.1.1 (ATP) and EC 6.5.1.2 (NAD). 
Indexing Annotation English:   do not confuse X ref POLYDEOXYRIBONUCLEOTIDE SYNTHETASES with X ref POLYRIBONUCLEOTIDE SYNTHETASE
History Note English:   98(77); for DNA LIGASES use POLYNUCLEOTIDE SYNTHETASES 1973-76 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   11522 
Unique Identifier:   D011088 

Occurrence in VHL:
 

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