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DeCS
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Descriptor English:
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DNA Modification Methylases
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Descriptor Spanish:
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Metilasas de Modificación del ADN
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Descriptor Portuguese:
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Metilases de Modificação do DNA
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Synonyms English:
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DNA Modification Methyltransferases
Modification Methylases
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Tree Number:
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D08.811.150.240
D08.811.913.555.500.350
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Definition English:
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Enzymes that are part of the restriction-modification systems. They are responsible for producing a species-characteristic methylation pattern, on either adenine or cytosine residues, in a specific short base sequence in the host cell's own DNA. This methylated sequence will occur many times in the host-cell DNA and remain intact for the lifetime of the cell. Any DNA from another species which gains entry into a living cell and lacks the characteristic methylation pattern will be recognized by the restriction endonucleases of similar specificity and destroyed by cleavage. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. |
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History Note English:
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1989
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Allowable Qualifiers English:
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Record Number:
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23613
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Unique Identifier:
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D015254
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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