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DeCS
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Descriptor English:
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DNA Restriction Enzymes
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Descriptor Spanish:
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Enzimas de Restricción del ADN
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Descriptor Portuguese:
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Enzimas de Restrição do DNA
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Synonyms English:
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Restriction Endonucleases
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Tree Number:
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D08.811.150.280
D08.811.277.352.335.350.300
D08.811.277.352.355.325.300
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Definition English:
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Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species-specific methylation pattern in the host cell's DNA. Cleavage yields random or specific double-stranded fragments with terminal 5'-phosphates. The function of restriction enzymes is to destroy any foreign DNA that invades the host cell. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. They are also used as tools for the systematic dissection and mapping of chromosomes, in the determination of base sequences of DNAs, and have made it possible to splice and recombine genes from one organism into the genome of another. EC 3.21.1. |
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Indexing Annotation English:
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DNA restriction enzyme used as a DNA marker: coord probably NIM with GENETIC MARKER (IM)
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See Related English:
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Polymorphism, Restriction Fragment Length
Restriction Mapping
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History Note English:
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79; was DNA RESTRICTION ENZYME 1978, was DNA RESTRICTION ENZYME see under ENDONUCLEASES 1975-77
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Allowable Qualifiers English:
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Record Number:
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23985
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Unique Identifier:
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D004262
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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