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DeCS
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Descriptor English:
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DNA Topoisomerases, Type II, Eukaryotic
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Descriptor Spanish:
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Topoisomerasas de ADN Tipo II Eucarióticas
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Descriptor Portuguese:
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DNA Topoisomerases Tipo II Eucarióticas
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Tree Number:
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D08.811.399.403.741.500
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Definition English:
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Eukaryotic enzymes of the DNA TOPOISOMERASES, TYPE II class that catalyze ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. These enzymes bring about relaxation of the supercoiled DNA and resolution of a knotted circular DNA duplex. Isozymes of the eukaryotic DNA topoisomerase II consist of homodimers of alpha or beta subunits. |
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History Note English:
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2002
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Allowable Qualifiers English:
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Record Number:
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36091
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Unique Identifier:
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D029081
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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