Search on: DNASE I 
Descriptors Found: 1
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Descriptor English:   Deoxyribonuclease I 
Descriptor Spanish:   Desoxirribonucleasa I 
Descriptor Portuguese:   Desoxirribonuclease I 
Synonyms English:   DNase I
Streptodornase  
Tree Number:   D08.811.277.352.335.350.250
Definition English:   An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. This catalyzes endonucleolytic cleavage of DNA yielding 5'-phosphodi- and oligonucleotide end-products. The enzyme has a preference for double-stranded DNA. 
Indexing Annotation English:   do not confuse X ref STREPTODORNASE with STREPTODORNASE AND STREPTOKINASE: see note there; DF: note short X ref
History Note English:   85; STREPTODORNASE was see DEOXYRIBONUCLEASES 1966-93 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   3873 
Unique Identifier:   D003850 

Occurrence in VHL:
 

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