Search on: DANTROLENE 
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Descriptor English:   Dantrolene 
Descriptor Spanish:   Dantroleno 
Descriptor Portuguese:   Dantroleno 
Tree Number:   D03.383.129.308.432.555.287
Definition English:   Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants. 
Pharmacological Action:   Muscle Relaxants, Central
 
History Note English:   80(75); was see under HYDANTOINS 1975-79 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
urine  
Record Number:   3639 
Unique Identifier:   D003620 

Occurrence in VHL:
 

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