Search on: DEPRENIL 
Descriptors Found: 1
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Descriptor English:   Selegiline 
Descriptor Spanish:   Selegilina 
Descriptor Portuguese:   Selegilina 
Synonyms English:   Deprenalin
Deprenil
Deprenyl  
Tree Number:   D02.092.471.683.915
Definition English:   A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl. 
Pharmacological Action:   Antiparkinson Agents
Monoamine Oxidase Inhibitors
Neuroprotective Agents
 
History Note English:   91(84); was see under PHENETHYLAMINES 1984-90; was DEPRENYL see under PHENETHYLAMINES 1979-83 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
urine  
Record Number:   22667 
Unique Identifier:   D012642 

Occurrence in VHL:
 

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