Search on: DESIPRAMINE 
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Descriptor English:   Desipramine 
Descriptor Spanish:   Desipramina 
Descriptor Portuguese:   Desipramina 
Synonyms English:   Desmethylimipramine  
Tree Number:   D03.494.240.281
Definition English:   A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors. 
Pharmacological Action:   Adrenergic Uptake Inhibitors
Antidepressive Agents, Tricyclic
Enzyme Inhibitors
 
History Note English:   65(63) 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
urine  
Record Number:   3911 
Unique Identifier:   D003891 

Occurrence in VHL:
 

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