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DIAZOOXONORLEUCINE
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DeCS
Descriptor
English
:
Diazooxonorleucine
Descriptor
Spanish
:
Diazooxonorleucina
Descriptor
Portuguese
:
Diazooxonorleucina
Tree Number:
D02.172.508
D12.125.213.568.175
Definition
English
:
An amino acid that inhibits phosphate-activated
glutaminase
and interferes with
glutamine
metabolism
. It is an antineoplastic antibiotic produced by an unidentified species of
Streptomyces
from Peruvian
soil
. (From Merck Index, 11th ed)
Pharmacological Action:
Antibiotics, Antineoplastic
Antimetabolites, Antineoplastic
History Note
English
:
91(65); was see under AZO COMPOUNDS 1965-90
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
urine
Record Number:
4009
Unique Identifier:
D003980
Occurrence in VHL
:
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