Search on: DIHYDROOROTATE OXIDASE 
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Descriptor English:   Dihydroorotate Oxidase 
Descriptor Spanish:   Dihidroorotato Oxidasa 
Descriptor Portuguese:   Diidrorotato Oxidase 
Tree Number:   D08.811.682.660.300
Definition English:   An enzyme that in the course of pyrimidine biosynthesis, catalyzes the oxidation of dihydro-orotic acid to orotic acid utilizing oxygen as the electron acceptor. This enzyme is a flavoprotein which contains both FLAVIN-ADENINE DINUCLEOTIDE and FLAVIN MONONUCLEOTIDE as well as iron-sulfur centers. EC 1.3.3.1. 
History Note English:   94; was DIHYDRO-OROTATE OXIDASE 1977-93 (see under OXIDOREDUCTASES 1977-90); DIHYDRO-OROTATE DEHYDROGENASE & OROTATE REDUCTASE were see DIHYDRO-OROTATE OXIDASE 1977-93 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   31730 
Unique Identifier:   D004081 

Occurrence in VHL:
 

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