Search on: DIZOCILPINE MALEATE 
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Descriptor English:   Dizocilpine Maleate 
Descriptor Spanish:   Maleato de Dizocilpina 
Descriptor Portuguese:   Maleato de Dizocilpina 
Synonyms English:   Dizocilpine  
Tree Number:   D02.455.426.559.847.181.384.380
D04.615.181.384.380
Definition English:   A potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) used mainly as a research tool. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role. Its use has been primarily limited to animal and tissue experiments because of its psychotropic effects. 
Indexing Annotation English:   DF: note short X
Pharmacological Action:   Excitatory Amino Acid Antagonists
Neuroprotective Agents
 
History Note English:   91 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
urine  
Record Number:   28911 
Unique Identifier:   D016291 

Occurrence in VHL:
 

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