DeCS Server - List Exact Term

Search on:	DOPAMINE RECEPTOR ANTAGONISTS
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DeCS

Descriptor English:

Dopamine Antagonists

Descriptor Spanish:

Antagonistas de Dopamina

Descriptor Portuguese:

Antagonistas de Dopamina

Synonyms English:

Dopamine Receptor Antagonists
Dopaminergic Antagonists

Tree Number:

Definition English:

Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME.

Indexing Annotation English:

DF: DOPAMINE ANTAG

History Note English:

Allowable Qualifiers English:

Record Number:

32275

Unique Identifier:

D018492

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