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DeCS
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Descriptor English:
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Hyperlipoproteinemia Type III
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Descriptor Spanish:
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Hiperlipoproteinemia Tipo III
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Descriptor Portuguese:
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Hiperlipoproteinemia Tipo III
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Synonyms English:
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Broad beta Disease
Dysbetalipoproteinemia
Dysbetalipoproteinemia, Familial
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Tree Number:
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C16.320.565.398.483
C18.452.584.500.500.644.485
C18.452.648.398.483
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Definition English:
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An autosomal recessively inherited disorder characterized by the accumulation of intermediate-density lipoprotein (IDL or broad-beta-lipoprotein). IDL has a CHOLESTEROL to TRIGLYCERIDES ratio greater than that of VERY-LOW-DENSITY LIPOPROTEINS. This disorder is due to mutation of APOLIPOPROTEIN E, a receptor-binding component of VLDL and CHYLOMICRONS, resulting in their reduced clearance and high plasma levels of both cholesterol and triglycerides. |
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History Note English:
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80
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Allowable Qualifiers English:
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Record Number:
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7133
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Unique Identifier:
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D006952
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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