DeCS Server - List Exact Term

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DeCS

Descriptor English:

Factor VIIIa

Descriptor Spanish:

Factor VIIIa

Descriptor Portuguese:

Fator VIIIa

Synonyms English:

Factor VIII, Activated
Factor VIII, Thrombin-Activated
Coagulation Factor VIIIa

Tree Number:

Definition English:

Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similar in structure and generation to factor Va.

Indexing Annotation English:

a blood coag factor; /defic = HEMOPHILIA

See Related English:

History Note English:

Allowable Qualifiers English:

Record Number:

24644

Unique Identifier:

D015944

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