Search on: FACTOR XIA 
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Descriptor English:   Factor XIa 
Descriptor Spanish:   Factor Xia 
Descriptor Portuguese:   Fator Xia 
Synonyms English:   Factor XI, Activated
Coagulation Factor XIa  
Tree Number:   D08.811.277.656.300.760.320
D12.776.124.125.425.320
D23.119.425.320
Definition English:   Activated form of factor XI. In the intrinsic pathway, Factor XI is activated to XIa by factor XIIa in the presence of cofactor HMWK; (HIGH MOLECULAR WEIGHT KININOGEN). Factor XIa then activates factor IX to factor IXa in the presence of calcium. 
Indexing Annotation English:   /defic = FACTOR XI DEFICIENCY
See Related English:   Coagulants
 
History Note English:   90 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   24647 
Unique Identifier:   D015945 

Occurrence in VHL: 		 

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