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FAS LIGAND PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
Fas Ligand Protein
Descriptor
Spanish
:
Proteína Ligando Fas
Descriptor
Portuguese
:
Proteína Ligante Fas
Synonyms
English
:
Antigens, CD178
CD178 Antigens
Tumor Necrosis Factor Ligand Superfamily Member 6
Tree Number:
D12.644.276.374.750.249
D12.644.276.972.249
D12.776.395.550.312
D12.776.467.374.750.249
D12.776.467.972.249
D12.776.543.550.312
D23.050.301.264.035.283
D23.101.100.110.282
D23.529.374.750.249
D23.529.972.249
Definition
English
:
A transmembrane protein belonging to the tumor
necrosis
factor superfamily that was originally discovered on
cells
of the lymphoid-myeloid lineage, including activated
T-LYMPHOCYTES
and NATURAL
KILLER CELLS
. It plays an important
role
in immune
homeostasis
and cell-mediated
toxicity
by binding to the FAS RECEPTOR and triggering
APOPTOSIS.
History Note
English
:
2007(1994)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
52293
Unique Identifier:
D053222
Occurrence in VHL
:
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