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DeCS
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Descriptor English:
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Fibroblast Growth Factor 1
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Descriptor Spanish:
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Factor 1 de Crecimiento de Fibroblasto
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Descriptor Portuguese:
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Fator 1 de Crescimento de Fibroblastos
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Synonyms English:
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Acidic Fibroblast Growth Factor
Class I Heparin-Binding Growth Factor
HBGF-1
Heparin-Binding Fibroblast Growth Factor Class I
Heparin-Binding Growth Factor, Class I
Fibroblast Growth Factor, Acidic
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Tree Number:
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D12.644.276.624.110
D12.776.467.624.110
D23.529.624.110
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Definition English:
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A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. It binds to HEPARIN, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 2). |
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Indexing Annotation English:
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DF: FGF1
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History Note English:
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2002(1991); for FIBROBLAST GROWTH FACTOR-1 use FIBROBLAST GROWTH FACTOR 1(NM) 1998-2001
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Allowable Qualifiers English:
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Record Number:
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28935
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Unique Identifier:
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D016220
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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