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GAP-43 PROTEIN
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DeCS
Descriptor
English
:
GAP-43 Protein
Descriptor
Spanish
:
Proteína GAP-43
Descriptor
Portuguese
:
Proteína GAP-43
Synonyms
English
:
B-50 Protein
Nerve Growth Cone Membrane Protein GAP-43
GAP-43
Neuromodulin
Growth-Associated Protein 43
Tree Number:
D12.776.395.550.400
D12.776.543.550.400
D12.776.641.400
Definition
English
:
A nervous tissue specific protein which is highly expressed in
NEURONS
during development and
NERVE REGENERATION
. It has been implicated in neurite outgrowth,
long-term potentiation
,
SIGNAL TRANSDUCTION
, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of
PROTEIN KINASE C.
History Note
English
:
98; use GAP-43 PROTEIN (NM) 1986-97
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
33491
Unique Identifier:
D019922
Occurrence in VHL
:
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