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INTERLEUKIN-1
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DeCS
Descriptor
English
:
Interleukin-1
Descriptor
Spanish
:
Interleucina-1
Descriptor
Portuguese
:
Interleucina-1
Synonyms
English
:
Lymphocyte-Activating Factor
IL-1
Tree Number:
D12.644.276.374.465.501
D12.644.276.374.500.400
D12.776.467.374.465.501
D12.776.467.374.500.400
D23.529.374.465.501
D23.529.374.500.400
Definition
English
:
A soluble factor produced by
MONOCYTES
;
MACROPHAGES
, and other
cells
which activates
T-lymphocytes
and potentiates their response to
mitogens
or
antigens
.
Interleukin-1
is a general term refers to either of the two distinct
proteins
,
INTERLEUKIN-1ALPHA
and
INTERLEUKIN-1BETA
. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.
Indexing Annotation
English
:
DF: IL 1 or IL1
See Related
English
:
Receptors, Interleukin-1
History Note
English
:
1990(1983)
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
29487
Unique Identifier:
D007375
Occurrence in VHL
:
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