Search on: INTERLEUKIN-18 
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Descriptor English:   Interleukin-18 
Descriptor Spanish:   Interleucina-18 
Descriptor Portuguese:   Interleucina-18 
Synonyms English:   Interferon-gamma-Inducing Factor
IFN-gamma-Inducing Factor
IL-18  
Tree Number:   D12.644.276.374.465.518
D12.776.467.374.465.518
D23.529.374.465.518
Definition English:   A cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK CELLS and CYTOTOXIC T-LYMPHOCYTES, and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity. 
Indexing Annotation English:   DF: IL18
History Note English:   99; use INTERLEUKIN-18 (NM) 1995-98 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use urine
Record Number:   33854 
Unique Identifier:   D020382 

Occurrence in VHL:
 

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