Search on: INTERLEUKIN-4 
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Descriptor English:   Interleukin-4 
Descriptor Spanish:   Interleucina-4 
Descriptor Portuguese:   Interleucina-4 
Synonyms English:   B-Cell Stimulatory Factor-1
IL-4
Mast Cell Growth Factor-2
B-Cell Growth Factor-I
Binetrakin  
Tree Number:   D12.644.276.374.465.504
D12.776.467.374.465.504
D23.529.374.465.504
Definition English:   A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells. 
Indexing Annotation English:   DF: IL 4 or IL4
Pharmacological Action:   Adjuvants, Immunologic
Antineoplastic Agents
Antirheumatic Agents
 
See Related English:   Histocompatibility Antigens Class II
 
History Note English:   90; B-CELL GROWTH FACTOR was see INTERLEUKIN-4 1990-96 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use urine
Record Number:   29470 
Unique Identifier:   D015847 

Occurrence in VHL:
 

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