Search on: MIXED CONNECTIVE TISSUE DISEASE 
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Descriptor English:   Mixed Connective Tissue Disease 
Descriptor Spanish:   Enfermedad Mixta del Tejido Conjuntivo 
Descriptor Portuguese:   Doença Mista do Tecido Conjuntivo 
Synonyms English:   Connective Tissue Disease, Mixed
Sharp Syndrome  
Tree Number:   C17.300.540
Definition English:   A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence. 
Indexing Annotation English:   disease entity: read definition & do not confuse with CONNECTIVE TISSUE DISEASES; DF: MCTD
History Note English:   79 
Allowable Qualifiers English:  
blood cerebrospinal fluid
chemically induced classification
congenital complications
diet therapy diagnosis
drug therapy economics
ethnology embryology
enzymology epidemiology
etiology genetics
history immunology
metabolism microbiology
mortality nursing
pathology prevention & control
physiopathology parasitology
psychology radiography
rehabilitation radionuclide imaging
radiotherapy surgery
therapy urine
ultrasonography veterinary
virology  
Record Number:   9137 
Unique Identifier:   D008947 

Occurrence in VHL:
 

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