Search on: MUSCLE RELAXANTS, CENTRAL 
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Descriptor English:   Muscle Relaxants, Central 
Descriptor Spanish:   Relajantes Musculares Centrales 
Descriptor Portuguese:   Relaxantes Musculares Centrais 
Synonyms English:   Centrally Acting Muscle Relaxants  
Tree Number:   D27.505.696.510
D27.505.696.663.700.600
D27.505.954.427.525
Definition English:   A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358) 
Indexing Annotation English:   refers to skeletal muscle relaxants only: smooth muscle relaxants = PARASYMPATHOLYTICS
See Related English:   Parasympatholytics
 
History Note English:   70; MUSCLE RELAXANTS was see under CURARE-LIKE AGENTS & MUSCLE RELAXANTS, CENTRAL & NEUROMUSCULAR DEPOLARIZING AGENTS 1970-74, was heading 1963-69 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications diagnostic use
economics history
immunology isolation & purification
metabolism pharmacology
pharmacokinetics poisoning
radiation effects supply & distribution
standards toxicity
therapeutic use urine
Record Number:   9315 
Unique Identifier:   D009125 

Occurrence in VHL:
 

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