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MYELINOLYSIS, CENTRAL PONTINE
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DeCS
Descriptor
English
:
Myelinolysis, Central Pontine
Descriptor
Spanish
:
Mielinólisis Pontino Central
Descriptor
Portuguese
:
Mielinólise Central da Ponte
Synonyms
English
:
Central Pontine Myelinolysis
Extrapontine Myelinolysis
Tree Number:
C10.228.140.163.560
C10.314.500
C18.452.132.560
Definition
English
:
A demyelinating condition affecting the
PONS
and characterized clinically by an acute progressive
QUADRIPLEGIA
;
DYSARTHRIA
; DYSPHAGIA; and alterations of
consciousness
. Pathologic features include prominent demyelination in the central
PONS
with sparing of
axons
and
neurons
. This condition is usually associated with systemic disorders such as
HYPONATREMIA
; chronic
ALCOHOLISM
;
LIVER FAILURE
; severe
BURNS
; malignant
NEOPLASMS
; hemorrhagic
PANCREATITIS
; HEMODIALYSIS; and
SEPSIS
. The rapid medical correction of
hyponatremia
has been cited as a cause of this condition. (From Adams et al., Principles of
Neurology
, 6th ed, pp1125-6)
History Note
English
:
1994
Allowable Qualifiers
English
:
blood
cerebrospinal fluid
chemically induced
classification
congenital
complications
diet therapy
diagnosis
drug therapy
economics
ethnology
embryology
enzymology
epidemiology
etiology
genetics
history
immunology
metabolism
microbiology
mortality
nursing
pathology
prevention & control
physiopathology
parasitology
psychology
radiography
rehabilitation
radionuclide imaging
radiotherapy
surgery
therapy
urine
ultrasonography
veterinary
virology
Record Number:
31291
Unique Identifier:
D017590
Occurrence in VHL
:
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