Search on: NEOPLASMS, SECOND PRIMARY 
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Descriptor English:   Neoplasms, Second Primary 
Descriptor Spanish:   Neoplasias Primarias Secundarias 
Descriptor Portuguese:   Segunda Neoplasia Primária 
Synonyms English:   Neoplasms, Therapy-Related
Neoplasms, Treatment-Related
Second Malignancy
Second Neoplasm
Second Primary Neoplasms
Neoplasms, Metachronous
Neoplasms, Metachronous Second Primary
Therapy-Associated Neoplasms
Therapy-Related Cancer
Treatment-Associated Neoplasms
Treatment-Related Cancer  
Tree Number:   C04.692
Definition English:   Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause. 
Indexing Annotation English:   a 2d or more neopl of same or different histol type at same or different sites: do not confuse with NEOPLASMS, MULTIPLE PRIMARY (see note there); often follows ther (note X refs); IM; coord with each specific histol type (IM) & each precoord organ/neopl term (IM); do not use /compl with specific multiple neopl terms to show multiplicity; Manual 24.4.1.7; differentiate from NEOPLASM METASTASIS (Manual 24.4.1.3+) & NEOPLASM RECURRENCE, LOCAL: Manual 24.4.1.5
See Related English:   Neoplasms, Multiple Primary
 
History Note English:   92 
Allowable Qualifiers English:  
blood blood supply
cerebrospinal fluid chemistry
chemically induced classification
congenital complications
diet therapy diagnosis
drug therapy economics
ethnology embryology
enzymology epidemiology
etiology genetics
history immunology
metabolism microbiology
mortality nursing
pathology prevention & control
physiopathology parasitology
psychology radiography
rehabilitation radionuclide imaging
radiotherapy secondary
secretion surgery
therapy ultrastructure
urine ultrasonography
veterinary virology
Record Number:   29936 
Unique Identifier:   D016609 

Occurrence in VHL:
 

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