Search on:
P-GLYCOPROTEIN
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
P-Glycoprotein
Descriptor
Spanish
:
P-Glicoproteína
Descriptor
Portuguese
:
Glicoproteína P
Synonyms
English
:
MDR1 Protein
Multidrug Resistance Protein 1
Tree Number:
D12.776.157.530.100.652.500
D12.776.157.530.450.074.500.500.750
D12.776.395.550.020.610.610
D12.776.543.550.192.610.610
D12.776.543.585.100.610.500
D12.776.543.585.450.074.500.500.750
Definition
English
:
A 170-kDa transmembrane glycoprotein from the superfamily of
ATP-BINDING CASSETTE TRANSPORTERS
. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many
ANTINEOPLASTIC AGENTS
. Overexpression of this glycoprotein is associated with multidrug resistance (see
DRUG RESISTANCE
, MULTIPLE).
Indexing Annotation
English
:
P-GLYCOPROTEINS is also available
Entry Combination - descr/qualif
English
:
P-Glycoprotein
/
analogs & derivatives
use
P-Glycoproteins
See Related
English
:
Drug Resistance, Multiple
History Note
English
:
99; use P-GLYCOPROTEIN 1995-98
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
32100
Unique Identifier:
D020168
Occurrence in VHL
:
Similar:
DeCS
SciELO
LILACS
LIS