Search on: PAIN INSENSITIVITY, CONGENITAL 
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Descriptor English:   Pain Insensitivity, Congenital 
Descriptor Spanish:   Insensibilidad Congénita al Dolor 
Descriptor Portuguese:   Insensibilidade Congênita à Dor 
Synonyms English:   Analgesia, Congenital
Pain Indifference, Congenital  
Tree Number:   C10.668.829.700
C16.320.775
Definition English:   A syndrome characterized by indifference to PAIN despite the ability to distinguish noxious from nonnoxious stimuli. Absent corneal reflexes and MENTAL RETARDATION may be associated. Familial forms with autosomal recessive and autosomal dominant patterns of inheritance have been described. (Adams et al., Principles of Neurology, 6th ed, p1343) 
Indexing Annotation English:   congenital insensitivity to pain with anhidrosis = HSAN TYPE IV see NEUROPATHIES, HEREDITARY SENSORY AND AUTONOMIC; DF: PAIN INSENSITIVITY CONGEN
See Related English:   Hereditary Sensory and Autonomic Neuropathies
 
History Note English:   96; was ANALGESIA, CONGENITAL 1964-95 (Prov 1964-72); PAIN INSENSITIVITY, CONGENITAL was see ANALGESIA, CONGENITAL 1973-95 
Allowable Qualifiers English:  
blood cerebrospinal fluid
chemically induced classification
complications diet therapy
diagnosis drug therapy
economics ethnology
embryology enzymology
epidemiology etiology
genetics history
immunology metabolism
microbiology mortality
nursing pathology
prevention & control physiopathology
parasitology psychology
radiography rehabilitation
radionuclide imaging radiotherapy
surgery therapy
ultrastructure urine
ultrasonography veterinary
virology  
Record Number:   23943 
Unique Identifier:   D000699 

Occurrence in VHL:
 

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