Search on: PHLEOMYCINS 
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Descriptor English:   Phleomycins 
Descriptor Spanish:   Fleomicinas 
Descriptor Portuguese:   Fleomicinas 
Tree Number:   D09.400.420.110.710
D12.644.233.110.710
Definition English:   Water-soluble, copper-containing low molecular weight polypeptides obtained from the culture medium of Streptomyces verticillus. They are specific inhibitors of DNA synthesis in bacteria and have been found to act as antitumor agents. They have also been used against rust fungi of plants. 
Pharmacological Action:   Antibiotics, Antineoplastic
Nucleic Acid Synthesis Inhibitors
 
History Note English:   91(81); was see under BLEOMYCINS 1981-90; was PHLEOMYCIN see under ANTIBIOTICS 1975-80 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
urine  
Record Number:   10886 
Unique Identifier:   D010692 

Occurrence in VHL:
 

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