Search on: PRENYLTRANSFERASE 
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Descriptor English:   Dimethylallyltranstransferase 
Descriptor Spanish:   Dimetilaliltranstransferasa 
Descriptor Portuguese:   Dimetilaliltranstransferase 
Synonyms English:   Farnesylpyrophosphate Synthetase
Geranylpyrophosphate Synthetase
Prenyltransferase
Dimethylallyltransferase  
Tree Number:   D08.811.913.225.400
Definition English:   An enzyme that, in the pathway of cholesterol biosynthesis, catalyzes the condensation of isopentenyl pyrophosphate and dimethylallylpyrophosphate to yield pyrophosphate and geranylpyrophosphate. The enzyme then catalyzes the condensation of the latter compound with another molecule of isopentenyl pyrophosphate to yield pyrophosphate and farnesylpyrophosphate. EC 2.5.1.1. 
History Note English:   97; was DIMETHYLALLYLTRANSFERASE 1979-96 (see under TRANSFERASES 1979-90) 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   4170 
Unique Identifier:   D004122 

Occurrence in VHL:
 

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