Search on: PROCOLLAGEN N-ENDOPEPTIDASE 
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Descriptor English:   Procollagen N-Endopeptidase 
Descriptor Spanish:   Procolágeno N-Endopeptidasa 
Descriptor Portuguese:   Procolágeno N-Endopeptidase 
Synonyms English:   Procollagen Peptidase  
Tree Number:   D08.811.277.656.300.480.664
D08.811.277.656.675.374.664
Definition English:   An extracellular endopeptidase which excises a block of peptides at the amino terminal, nonhelical region of the procollagen molecule with the formation of collagen. Absence or deficiency of the enzyme causes accumulation of procollagen which results in the inherited connective tissue disorder--dermatosparaxis. EC 3.4.24.14. 
History Note English:   97; was PROCOLLAGEN PEPTIDASE 1977-96 (see under ENDOPEPTIDASES 1977-90) 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   11784 
Unique Identifier:   D011348 

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