Search on: PROCOLLAGEN-LYSINE, 2-OXOGLUTARATE 5-DIOXYGENASE 
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Descriptor English:   Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 
Descriptor Spanish:   Procolágeno-Lisina 2-Oxoglutarato 5-Dioxigenasa 
Descriptor Portuguese:   Procolágeno-Lisina 2-Oxoglutarato 5-Dioxigenase 
Synonyms English:   Lysine 2-Oxoglutarate Dioxygenase
Protocollagen Lysyl Hydroxylase
Lysine Hydroxylase  
Tree Number:   D08.811.682.690.708.660
Definition English:   A mixed-function oxygenase that catalyzes the hydroxylation of peptidyllysine, usually in protocollagen, to peptidylhydroxylysine. The enzyme utilizes molecular oxygen with concomitant oxidative decarboxylation of the cosubstrate 2-oxoglutarate to succinate. EC 1.14.11.4. 
Indexing Annotation English:   DF: note short X ref
History Note English:   92; was LYSINE HYDROXYLASE 1977-91 (see under HYDROXYLASES 1977-90) 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   30382 
Unique Identifier:   D008240 

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