Search on: PROGRESSIVE NONFLUENT APHASIA 
Descriptors Found: 1
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 1 / 1 DeCS     
Descriptor English:   Aphasia, Primary Progressive 
Descriptor Spanish:   Afasia Progresiva Primaria 
Descriptor Portuguese:   Afasia Primária Progressiva 
Synonyms English:   Mesulam Syndrome
Progressive Nonfluent Aphasia  
Tree Number:   C10.228.140.380.132
C10.597.606.150.500.800.100.155
C23.888.592.604.150.500.800.100.155
F03.087.400.125
Definition English:   A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26) 
Indexing Annotation English:   a clin entity: do not confuse with descriptions of the progression of aphasia in case reports
History Note English:   1996 
Allowable Qualifiers English:  
blood cerebrospinal fluid
chemically induced classification
complications diet therapy
diagnosis drug therapy
economics ethnology
enzymology epidemiology
etiology genetics
history immunology
metabolism microbiology
mortality nursing
pathology prevention & control
physiopathology parasitology
psychology radiography
rehabilitation radionuclide imaging
surgery therapy
urine ultrasonography
virology  
Record Number:   32833 
Unique Identifier:   D018888 

Occurrence in VHL:
 

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