Search on: PROTO-ONCOGENE PROTEINS C-FES 
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Descriptor English:   Proto-Oncogene Proteins c-fes 
Descriptor Spanish:   Proteínas Proto-Oncogénicas c-fes 
Descriptor Portuguese:   Proteínas Proto-Oncogênicas c-fes 
Synonyms English:   c-fes Proteins
fes Proto-Oncogene Proteins
fps Proto-Oncogene Protein  
Tree Number:   D08.811.913.696.620.682.725.300
D12.776.624.664.700.177
Definition English:   Proto-oncogene proteins fes are protein-tyrosine kinases with a central SH2 DOMAIN. It has been implicated in SIGNAL TRANSDUCTION PATHWAYS for CELL DIFFERENTIATION of a variety of cell types including MYELOID PROGENITOR CELLS. Fes proto-oncogene proteins also bind TUBULIN and promotes MICROTUBULE assembly. 
History Note English:   2006(1986) 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   50731 
Unique Identifier:   D051578 

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