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PYRUVATE CARBOXYLASE
Descriptors Found:
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DeCS
Descriptor
English
:
Pyruvate Carboxylase
Descriptor
Spanish
:
Piruvato Carboxilasa
Descriptor
Portuguese
:
Piruvato Carboxilase
Tree Number:
D08.811.464.257.500
Definition
English
:
A biotin-dependent enzyme belonging to the ligase
family
that catalyzes the addition of
CARBON DIOXIDE
to pyruvate. It is occurs in both
plants
and
animals
. Deficiency of this enzyme causes severe psychomotor retardation and
ACIDOSIS
, LACTIC in infants. EC 6.4.1.1.
Entry Combination - descr/qualif
English
:
Pyruvate Carboxylase
/
deficiency
use
Pyruvate Carboxylase Deficiency Disease
See Related
English
:
Pyruvate Carboxylase Deficiency Disease
History Note
English
:
74
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
12203
Unique Identifier:
D011766
Occurrence in VHL
:
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