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DeCS
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Descriptor English:
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Receptors, Aryl Hydrocarbon
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Descriptor Spanish:
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Receptores de Hidrocarburo de Aril
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Descriptor Portuguese:
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Receptores de Hidrocarboneto Arílico
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Synonyms English:
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Aryl Hydrocarbon Receptors
AH Receptors
Dioxin Receptors
Receptors, AH
Receptors, Dioxin
TCDD Receptors
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Tree Number:
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D12.776.826.480
D12.776.930.662
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Definition English:
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Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected. |
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Indexing Annotation English:
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DF: RECEPT AH
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History Note English:
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94; was ARYL HYDROCARBON RECEPTOR (NM) 1981-93; 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN RECEPTOR was (NM) 1979-93
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Allowable Qualifiers English:
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Record Number:
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31140
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Unique Identifier:
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D018336
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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