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RECEPTORS, INTERLEUKIN-1 TYPE II
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DeCS
Descriptor
English
:
Receptors, Interleukin-1 Type II
Descriptor
Spanish
:
Receptores Tipo II de Interleucina-1
Descriptor
Portuguese
:
Receptores Tipo II de Interleucina-1
Synonyms
English
:
Antigens, CDw121b
CDw121b Antigens
Interleukin-1 Receptor Type II
Tree Number:
D12.776.543.750.705.852.420.300.750
D23.050.301.264.035.699
D23.101.100.110.699
Definition
English
:
An
interleukin-1
receptor subtype that competes with the
INTERLEUKIN-1
RECEPTOR TYPE I for binding to
INTERLEUKIN-1ALPHA
and
INTERLEUKIN-1BETA
. The
interleukin-1
type II receptor appears to lack
signal transduction
capability. Therefore it may act as a "decoy" receptor that modulates the activity of its
ligands
. Both membrane-bound and soluble
forms
of the receptor have been identified.
History Note
English
:
2007(1996)
Allowable Qualifiers
English
:
administration & dosage
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
chemistry
classification
drug effects
deficiency
genetics
history
immunology
isolation & purification
metabolism
physiology
radiation effects
therapeutic use
ultrastructure
Record Number:
52345
Unique Identifier:
D053574
Occurrence in VHL
:
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