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RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL
Descriptors Found:
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DeCS
Descriptor
English
:
Ryanodine Receptor Calcium Release Channel
Descriptor
Spanish
:
Canal Liberador de Calcio Receptor de Rianodina
Descriptor
Portuguese
:
Canal de Liberação de Cálcio do Receptor de Rianodina
Synonyms
English
:
Calcium-Ryanodine Receptor Complex
Ryanodine Receptors
RyR1
Tree Number:
D12.776.157.530.400.150.800
D12.776.210.500.800
D12.776.543.550.425.150.800
D12.776.543.585.400.150.800
Definition
English
:
A tetrameric
calcium
release channel in the
SARCOPLASMIC RETICULUM
membrane of smooth
muscle cells
, acting oppositely to
SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES
. It is important in skeletal and cardiac excitation-contraction coupling and studied by using
RYANODINE
. Abnormalities are implicated in ARRHYTHMIAS, CARDIAC and
MUSCULAR DISEASES
.
History Note
English
:
98; use RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL (NM) 1985-97
Allowable Qualifiers
English
:
administration & dosage
adverse effects
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
33489
Unique Identifier:
D019837
Occurrence in VHL
:
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