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SELF TOLERANCE
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DeCS
Descriptor
English
:
Self Tolerance
Descriptor
Spanish
:
Autotolerancia
Descriptor
Portuguese
:
Tolerância a Antígenos Próprios
Tree Number:
G04.610.484.800
Definition
English
:
The normal lack of the ability to produce an immunological response to autologous (self)
antigens
. A breakdown of
self tolerance
leads to
autoimmune diseases
. The ability to recognize the difference between self and non-self is the prime function of the
immune system.
Indexing Annotation
English
:
a form of
immune tolerance
See Related
English
:
Autoimmune Diseases
Clonal Anergy
Clonal Deletion
History Note
English
:
94
Allowable Qualifiers
English
:
drug effects
ethics
genetics
immunology
physiology
radiation effects
Record Number:
31052
Unique Identifier:
D017634
Occurrence in VHL
:
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