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T4 ANTIGENS, T-CELL
Descriptors Found:
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DeCS
Descriptor
English
:
Antigens, CD4
Descriptor
Spanish
:
Antígenos CD4
Descriptor
Portuguese
:
Antígenos CD4
Synonyms
English
:
CD4 Antigens
CD4 Molecule
T4 Antigens, T-Cell
CD4 Receptors
Receptors, CD4
Tree Number:
D12.776.543.750.705.852.420.810.500
D12.776.543.750.925.700.025
D23.050.301.264.035.104
D23.050.301.264.894.100
D23.101.100.110.104
D23.101.100.894.100
Definition
English
:
55-kDa
antigens
found on HELPER-INDUCER
T-LYMPHOCYTES
and on a variety of other immune cell types. CD4
antigens
are members of the immunoglobulin supergene
family
and are implicated as associative recognition
elements
in
MAJOR HISTOCOMPATIBILITY COMPLEX
class II-restricted immune responses. On
T-lymphocytes
they define the helper/inducer subset. CD4
antigens
also serve as
INTERLEUKIN-15
receptors and bind to the
HIV
receptors, binding directly to the
HIV ENVELOPE PROTEIN GP120.
Indexing Annotation
English
:
for hematodermic CD4/CD56 neoplasm use
LYMPHOMA
, NON-HODGKIN
See Related
English
:
CD4-CD8 Ratio
HIV Envelope Protein gp120
History Note
English
:
90; was CD4 ANTIGENS see ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1989
Allowable Qualifiers
English
:
administration & dosage
adverse effects
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
contraindications
drug effects
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
poisoning
radiation effects
toxicity
therapeutic use
ultrastructure
urine
Record Number:
24525
Unique Identifier:
D015704
Occurrence in VHL
:
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