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T4 CELLS
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DeCS
Descriptor
English
:
CD4-Positive T-Lymphocytes
Descriptor
Spanish
:
Linfocitos T CD4-Positivos
Descriptor
Portuguese
:
Linfócitos T CD4-Positivos
Synonyms
English
:
T4 Cells
T4 Lymphocytes
Tree Number:
A11.118.637.555.567.569.200
A15.145.229.637.555.567.569.200
A15.382.490.555.567.569.200
Definition
English
:
A critical subpopulation of
T-lymphocytes
involved in the induction of most immunological functions. The
HIV
virus has selective
tropism
for the T4 cell which expresses the CD4 phenotypic marker, a receptor for
HIV
. In fact, the key element in the profound
immunosuppression
seen in
HIV
infection
is the depletion of this subset of
T-lymphocytes.
Indexing Annotation
English
:
subpopulations: index specifics if available or coordinate
CD4-POSITIVE T-LYMPHOCYTES
with
T-LYMPHOCYTE SUBSETS
; count: coordinate IM with
CD4 LYMPHOCYTE COUNT
(NIM)
See Related
English
:
Acquired Immunodeficiency Syndrome
Antigens, CD4
CD4-CD8 Ratio
T-Lymphocytopenia, Idiopathic CD4-Positive
History Note
English
:
95; was T4 LYMPHOCYTES 1989-94
Allowable Qualifiers
English
:
chemistry
classification
cytology
drug effects
enzymology
immunology
metabolism
microbiology
pathology
physiology
parasitology
radiography
radiation effects
radionuclide imaging
secretion
transplantation
ultrastructure
ultrasonography
virology
Record Number:
23747
Unique Identifier:
D015496
Occurrence in VHL
:
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DeCS
SciELO
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