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TATA-BOX-BINDING PROTEIN
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DeCS
Descriptor
English
:
TATA-Box Binding Protein
Descriptor
Spanish
:
Proteína de Unión a TATA-Box
Descriptor
Portuguese
:
Proteína de Ligação a TATA-Box
Synonyms
English
:
TATA-Box-Binding Protein
Tree Number:
D12.776.260.775.374
D12.776.260.775.875.750.500
D12.776.930.930.374
D12.776.930.930.875.750.500
Definition
English
:
A general transcription factor that plays a major
role
in the activation of eukaryotic
genes
transcribed by
RNA
POLYMERASES. It binds specifically to the
TATA BOX
promoter element, which lies close to the position of transcription initiation in
RNA
transcribed by
RNA POLYMERASE II
. Although considered a principal component of
TRANSCRIPTION FACTOR TFIID
it also takes part in general transcription factor complexes involved in
RNA POLYMERASE I
and
RNA POLYMERASE III
transcription.
History Note
English
:
2003; use TATA-BOX BINDING PROTEIN (NM) 1992-2002
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
37432
Unique Identifier:
D035181
Occurrence in VHL
:
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