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TNF
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DeCS
Descriptor
English
:
Tumor Necrosis Factors
Descriptor
Spanish
:
Factores de Necrosis Tumoral
Descriptor
Portuguese
:
Fatores de Necrose Tumoral
Synonyms
English
:
TNF
Tree Number:
D12.644.276.374.750
D12.644.276.972
D12.776.467.374.750
D12.776.467.972
D23.529.374.750
D23.529.972
Definition
English
:
A
family
of
proteins
that were originally identified by their ability to cause
NECROSIS
of
NEOPLASMS
. Their necrotic effect on
cells
is mediated through TUMOR
NECROSIS
FACTOR RECEPTORS which induce
APOPTOSIS.
History Note
English
:
2005
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
38737
Unique Identifier:
D048069
Occurrence in VHL
:
Similar:
DeCS
SciELO
LILACS
LIS