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DeCS
Descriptor
English
:
Tosylphenylalanyl Chloromethyl Ketone
Descriptor
Spanish
:
Clorometilcetona de Tosilfenilalanila
Descriptor
Portuguese
:
Tosilfenilalanil Clorometil Cetona
Synonyms
English
:
Chlorophenyltosylamidobutanone
Tosylphenylalanyl Chloromethane
TPCK
Tree Number:
D02.455.426.559.389.832.710
D02.886.590.887.660
D12.125.065.930
Definition
English
:
An inhibitor of
Serine Endopeptidases
. Acts as alkylating agent and is known to interfere with the translation process.
Pharmacological Action:
Alkylating Agents
Protein Synthesis Inhibitors
Serine Proteinase Inhibitors
History Note
English
:
91(75); was see under AMINO ACID CHLOROMETHYL KETONES 1977-90; was see under PHENYLALANINE 1975-76
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
urine
Record Number:
14500
Unique Identifier:
D014108
Occurrence in VHL
:
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DeCS
SciELO
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